DigiONE Pilot
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The project DigiONE (DIGItal Oncology Network for Europe) is an industry-funded pilot project aiming to build a federated digital research network. It links high-quality routine clinical data with molecular data from six leading cancer centres in Europe: Frankfurt, Leeds, Maastricht, Oslo, San Raffaele (Milan), and Saint-Luc (Brussels).
The digital infrastructure is based on the international Minimal Essential Description of Cancer (MEDOC) consensus, providing near real-time standardized descriptions of diagnoses, biomarkers, treatments, and outcomes. MEDOC covers the full patient journey from diagnosis to outcome and includes all major inclusion and exclusion criteria, creating a unique resource for high-quality real-world evidence (RWE) and care quality management.
For harmonisation and analysis, interoperability standards and tools from the Observational Health Data Sciences and Informatics (OHDSI) community are applied. Privacy-preserving analysis is performed in a federated way using Vantage6, enabling large-scale clinical research without centralising sensitive patient data.
In Frankfurt, the project is conducted in collaboration with the University Cancer Center (UCT), the Institute of Medical Informatics (IMI), and the Institute of Digital Medicine and Clinical Data Science (IDMKD).
Type of participation: Project participation (Project lead: DigiCore Europe).
Funding: Industry-funded pilot project, supported by IQVIA and Illumina.
