Komorbiditäten bei kolorektalem Karzinom
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The study “Prevalence and distribution of comorbidities in patients with colorectal cancer: A multicenter, retrospective observational study” is conducted with support of the DKTK Clinical Data Science Group in collaboration with the Clinical Communication Platform (CCP) of the German Cancer Consortium (DKTK). Four German university hospitals participate (Frankfurt, Hanover, Munich LMU and Mannheim).
The aim of the study is to investigate the distribution, burden, and profiles of comorbidities in patients with colorectal cancer (CRC) and their impact on therapies and outcomes (especially overall survival). Although comorbidities are common in patients with CRC, there is little data available in Germany. To carry out the project, two different data sources (tumor documentation data and service billing data according to §21 KEntG) are linked and fed into a federated analysis via the CCP infrastructure. The analysis will be stratified along age groups, sex and tumor stage at the time of diagnosis.
The study is led by Dr. Daniel Maier (Frankfurt) together with PD Dr. Karin Berger-Thürmel (Munich LMU). Other participating site partners are Selina Becht (Munich LMU), Prof. Dr. Tianzuo Zhan (Mannheim), and Dr. Fabian Ecke (Hanover).
